" /> Procollagen-Proline Dioxygenase - CISMeF





Preferred Label : Procollagen-Proline Dioxygenase;

NCIt synonyms : Prolyl 4-Hydroxylase; Collagen Proline Hydroxylase; Proline Hydroxylase; Protocollagen Hydroxylase; Prolylprotocollagen Dioxygenase; Protocollagen Proline 4-Hydroxylase; Protocollagen Prolyl Hydroxylase; Prolyl-Glycyl-Peptide, 2-Oxoglutarate:Oxygen Oxidoreductase, 4-Hydroxylating; Hydroxylase, Collagen Proline; Prolylprotocollagen Hydroxylase; Prolyl Hydroxylase; EC 1.14.11.2; Procollagen-Proline 4-Dioxygenase; Proline,2-Oxoglutarate 4-Dioxygenase; Protocollagen Proline Dioxygenase; Proline, 2-Oxoglutarate Dioxygenase; Proline Protocollagen Hydroxylase; Protocollagen Proline Hydroxylase; Peptidyl Proline Hydroxylase; P4H;

NCIt definition : A tetrameric enzyme complex that catalyzes the post-translational formation of 4-hydroxyproline in the amino acid sequence -Xaa-Pro-Gly-, which is found in collagens and other proteins. The enzyme complex is comprised of two alpha chains and two beta chains. There are 3 separate genes that encode 3 distinct alpha proteins, prolyl 4-hydroxylase subunit alpha-1, -2 and -3. The beta chain is protein disulfide-isomerase.;

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12/05/2024


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