Procollagen-Proline dioxygenase

Preferred Label : Procollagen-Proline dioxygenase;

MeSH definition : A mixed-function oxygenase that catalyzes the hydroxylation of a prolyl-glycyl containing peptide, usually in PROTOCOLLAGEN, to a hydroxyprolylglycyl-containing-peptide. The enzyme utilizes molecular OXYGEN with a concomitant oxidative decarboxylation of 2-oxoglutarate to SUCCINATE. The enzyme occurs as a tetramer of two alpha and two beta subunits. The beta subunit of procollagen-proline dioxygenase is identical to the enzyme PROTEIN DISULFIDE-ISOMERASES.;

MeSH synonym : dioxygenase, procollagen-proline; hydroxylase, protocollagen prolyl; procollagen prolyl 4 hydroxylase; procollagen prolyl 4-hydroxylase; prolyl hydroxylase, protocollagen; prolyl 4-hydroxylase, procollagen; protocollagen prolyl hydroxylase; 4-hydroxylase, procollagen prolyl; procollagen proline dioxygenase;

CISMeF synonym : 4-dioxygenase, proline,2-oxoglutarate; 4-hydroxylase, prolyl; hydroxylase, peptidyl prolyl; hydroxylase, proline; hydroxylase, prolyl; proline,2 oxoglutarate 4 dioxygenase; prolyl 4 hydroxylase; prolyl hydroxylase, peptidyl;

MeSH CAS label : Procollagen-L-proline,2-oxoglutarate:oxygen oxidoreductase;

MeSH Related Number : 9028-06-2 (CAS);

Registry Number MeSH : EC 1.14.11.2;

Wikipedia link : https://en.wikipedia.org/wiki/Procollagen-proline dioxygenase;

Is substance : O;

UNII : EC 1.14.11.2;

Details

Origin ID

D011393;

UMLS CUI

C0033384;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Procollagen-Proline Dioxygenase [NCIt concept]
- Procollagen-proline,2-oxoglutarate 4-dioxygenase (substance) [SNOMED CT concept]
- peptidyl-proline 4-dioxygenase activity [GO term]
- procollagen-proline,2-oxoglutarate 4-dioxygenase [SNOMED Notion]
Indexing information
- ((2-hydroxy-4-oxo-6,7,8,9-tetrahydro-4H,5H-10-thia-1,4a-diazabenzo(a)azulene-3-carbonyl)amino)acetic acid [MeSH Supplementary Concept]
- (2,2'-bipyridine)-5,5'-dicarboxylic acid [MeSH Supplementary Concept]
- (2,2'-bipyridine)-5-carboxylic acid [MeSH Supplementary Concept]
- 1-(5-chloro-6-(trifluoromethoxy)-1H-benzoimidazol-2-yl)-1H-pyrazole-4-carboxylic acid [MeSH Supplementary Concept]
- 2,7,8-trihydroxyanthraquinone [MeSH Supplementary Concept]
- 2-amino-4-methylsulfanylbutyric acid 4-methoxy-6-(4-methoxybenzylamino)-2,2-dimethylchroman-3-yl ester [MeSH Supplementary Concept]
- 5-azidopyridine-2-carboxylic acid [MeSH Supplementary Concept]
- FG 0041 [MeSH Supplementary Concept]
- coumalic acid [MeSH Supplementary Concept]
- diethyl 2,4-pyridinedicarboxylic acid [MeSH Supplementary Concept]
- dipicolinic acid [MeSH Supplementary Concept]
- fibrostatin C [MeSH Supplementary Concept]
- lufironil [MeSH Supplementary Concept]
- ribosyl-ribosyladenine [MeSH Supplementary Concept]
- vineomycin A1 [MeSH Supplementary Concept]
Record concept(s)
- Procollagen-Proline dioxygenase [MeSH concept]
Related MeSH Supplementary Concept(s)
- LEPREL1 protein, mouse [MeSH Supplementary Concept]
- Ofd1 protein, S pombe [MeSH Supplementary Concept]
- Ogfod1 protein, mouse [MeSH Supplementary Concept]
- P3H2 protein, human [MeSH Supplementary Concept]
- P4HA1 protein, human [MeSH Supplementary Concept]
- P4HA3 protein, human [MeSH Supplementary Concept]
- P4HB protein, human [MeSH Supplementary Concept]
- P4ha1 protein, mouse [MeSH Supplementary Concept]
- P4ha3 protein, mouse [MeSH Supplementary Concept]
- P4hb protein, mouse [MeSH Supplementary Concept]
- P4hb protein, rat [MeSH Supplementary Concept]
- PHD1 protein, mouse [MeSH Supplementary Concept]
- PHD3 protein, mouse [MeSH Supplementary Concept]
- Phy-1 protein, brugia malayi [MeSH Supplementary Concept]
- hif prolyl hydroxylase, drosophila [MeSH Supplementary Concept]
- proline, 2-oxoglutarate 3-dioxygenase [MeSH Supplementary Concept]
- prolyl hydroxylase domain protein 2, rat [MeSH Supplementary Concept]
See also
- protein Disulfide-Isomerases [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Procollagen-Proline Dioxygenase [NCIt concept]
- Procollagen-proline,2-oxoglutarate 4-dioxygenase (substance) [SNOMED CT concept]
- procollagen-proline,2-oxoglutarate 4-dioxygenase [SNOMED Notion]

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