Small G Protein

Preferred Label : Small G Protein;

NCIt definition : A class of small GTP-binding regulatory proteins regulated by G protein coupled receptors that act as switches in signal transduction pathways. The nature of the nucleotide bound to the protein determines its activity: GTP in the active state, GDP in the inactive state. The prototype for this class of proteins is the cellular proto-oncogene RAS.;

Détails

Origin ID

C18277;

UMLS CUI

C0751984;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- monomeric GTP-Binding proteins [MeSH Descriptor]
- monomeric GTP-Binding proteins [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Signaling Pathway Gene [NCIt concept]
gene_product_has_biochemical_function
- GTPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- GTP Binding [NCIt concept]
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients