GTPase - CISMeF

Preferred Label : GTPase;

NCIt synonyms : Guanosinetriphosphatase;

NCIt definition : Proteins that hydrolyze guanine triphosphate to yield guanine diphosphate. This is a class of proteins that belongs to a family of high energy phosphate hydrolases. Members of this family play major roles in biological signal transduction pathways.;

Details

Origin ID

C16650;

UMLS CUI

C0018296;

Biochemical function of gene products
- ADP-Ribosylation Factor 1 [NCIt concept]
- ADP-Ribosylation Factor 6 [NCIt concept]
- ADP-Ribosylation Factor-Like Protein 8B [NCIt concept]
- ADP-Ribosylation Factor-Related Protein 1 [NCIt concept]
- Atlastin-1 [NCIt concept]
- Cell Division Control Protein 42 Homolog [NCIt concept]
- Dexamethasone-Induced RAS-Related Protein 1 [NCIt concept]
- Dynamin-1 [NCIt concept]
- Dynamin-1-Like Protein [NCIt concept]
- Dynamin-2 [NCIt concept]
- Dynamin-Like 120 kDa Protein, Mitochondrial [NCIt concept]
- E3 Ubiquitin-Protein Ligase TRIM23 [NCIt concept]
- Elongation Factor 1 [NCIt concept]
- Elongation Factor 1-Alpha 1 [NCIt concept]
- Elongation Factor 1-Alpha 2 [NCIt concept]
- Elongation Factor 1-Beta [NCIt concept]
- Elongation Factor 1-Delta [NCIt concept]
- Elongation Factor 2 [NCIt concept]
- Elongation Factor G, Mitochondrial [NCIt concept]
- Eukaryotic Peptide Chain Release Factor GTP-Binding Subunit ERF3A [NCIt concept]
- Eukaryotic Translation Initiation Factor 5 [NCIt concept]
- GTP Cyclohydrolase 1 [NCIt concept]
- GTP-Binding Nuclear Protein Ran [NCIt concept]
- GTP-Binding Protein Di-Ras3 [NCIt concept]
- GTP-Binding Protein RAD [NCIt concept]
- GTP-Binding Protein Rheb [NCIt concept]
- GTP-Binding Protein Rit1 [NCIt concept]
- GTP-Binding Protein SAR1b [NCIt concept]
- GTPase HRas [NCIt concept]
- GTPase KRas [NCIt concept]
- GTPase Nras [NCIt concept]
- Guanine Nucleotide-Binding Protein G(i) Subunit Alpha-1 [NCIt concept]
- Guanine Nucleotide-Binding Protein G(i) Subunit Alpha-2 [NCIt concept]
- Guanine Nucleotide-Binding Protein G(k) Subunit Alpha [NCIt concept]
- Guanine Nucleotide-Binding Protein G(o) Subunit Alpha [NCIt concept]
- Guanine Nucleotide-Binding Protein G(q) Subunit Alpha [NCIt concept]
- Guanine Nucleotide-Binding Protein G(s) Subunit Alpha Isoforms Short [NCIt concept]
- Guanine Nucleotide-Binding Protein G(s) Subunit Alpha Isoforms XLas [NCIt concept]
- Guanine Nucleotide-Binding Protein G(z) Subunit Alpha [NCIt concept]
- Guanine Nucleotide-Binding Protein Subunit Alpha-11 [NCIt concept]
- Guanine Nucleotide-Binding Protein Subunit Alpha-12 [NCIt concept]
- Guanine Nucleotide-Binding Protein Subunit Alpha-13 [NCIt concept]
- Guanylate-Binding Protein 1 [NCIt concept]
- Guanylate-Binding Protein 2 [NCIt concept]
- Immunity-Related GTPase Family M Protein [NCIt concept]
- Interferon-Induced GTP-Binding Protein Mx1 [NCIt concept]
- Interferon-Induced GTP-Binding Protein Mx2 [NCIt concept]
- Mitofusin-2 [NCIt concept]
- RAS Superfamily Protein [NCIt concept]
- RAS-Related GTP-Binding Protein A [NCIt concept]
- RAS-Related Protein Rap-1A [NCIt concept]
- Rab-Like Protein 3 [NCIt concept]
- Ras-Like Protein Family Member 10A [NCIt concept]
- Ras-Related C3 Botulinum Toxin Substrate 1 [NCIt concept]
- Ras-Related C3 Botulinum Toxin Substrate 2 [NCIt concept]
- Ras-Related C3 Botulinum Toxin Substrate 3 [NCIt concept]
- Ras-Related GTP-Binding Protein C [NCIt concept]
- Ras-Related GTP-Binding Protein D [NCIt concept]
- Ras-Related Protein M-Ras [NCIt concept]
- Ras-Related Protein R-Ras [NCIt concept]
- Ras-Related Protein R-Ras2 [NCIt concept]
- Ras-Related Protein Rab-12 [NCIt concept]
- Ras-Related Protein Rab-23 [NCIt concept]
- Ras-Related Protein Rab-27A [NCIt concept]
- Ras-Related Protein Rab-35 [NCIt concept]
- Ras-Related Protein Rab-44 [NCIt concept]
- Ras-Related Protein Rab-5A [NCIt concept]
- Ras-Related Protein Rab-5B [NCIt concept]
- Ras-Related Protein Rab-5C [NCIt concept]
- Ras-Related Protein Rab-6B [NCIt concept]
- Ras-Related Protein Rab-7a [NCIt concept]
- Ras-Related Protein Rab-8A [NCIt concept]
- Ras-Related Protein Ral-A [NCIt concept]
- Ras-Related Protein Ral-B [NCIt concept]
- Ras-Related Protein Rap-2a [NCIt concept]
- Rho-Related GTP-Binding Protein RhoB [NCIt concept]
- Rho-Related GTP-Binding Protein RhoC [NCIt concept]
- Rho-Related GTP-Binding Protein RhoH [NCIt concept]
- Rho-Related GTP-Binding Protein RhoJ [NCIt concept]
- Rho-Related GTP-Binding Protein RhoU [NCIt concept]
- Septin-5 [NCIt concept]
- Septin-8 [NCIt concept]
- Small G Protein [NCIt concept]
- Transforming Protein RhoA [NCIt concept]
- p21 RAS Protein [NCIt concept]
- tRNA Modification GTPase GTPBP3, Mitochondrial [NCIt concept]
Currated CISMeF NLP mapping
- GTP phosphohydrolases [MeSH concept]
- gtp phosphohydrolases [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GTP phosphohydrolases [MeSH concept]
- gtp phosphohydrolases [MeSH Descriptor]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- GTPase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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