Serine/Threonine-Protein Phosphatase 2A Activator

Preferred Label : Serine/Threonine-Protein Phosphatase 2A Activator;

NCIt synonyms : Protein Phosphatase 2A Regulatory Subunit B Prime; PR53; EC 5.2.1.8; PPP2R4; PP2A Subunit B Prime; PTPA; Phosphotyrosyl Phosphatase Activator; Protein Phosphatase 2A Regulatory Subunit PR53; Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit B Prime; PP2A, Subunit B Prime, PR53 Isoform; PP2A; Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit 4; Protein Phosphatase-2A Regulatory Subunit-PR53; Protein Phosphatase 2 Regulatory Subunit 4; PP2A Subunit B Isoform PR53; PP2A, Subunit B', PR53 Isoform; Serine/Threonine-Protein Phosphatase 2A Regulatory Subunit B';

NCIt definition : Serine/threonine-protein phosphatase 2A activator (358 aa, 41 kDa) is encoded by the human PTPA gene. This protein plays a role in both the modulation of protein phosphatase 2A activity and protein folding.;

NCIt note : Protein Phosphatase 2A Regulatory Subunit PR53 is a specific and reversible phosphotyrosyl phosphatase activator of heterodimeric PP2A core enzyme in the presence of ATP and Mg( 2). Implicated in negative control of cell growth and division.;

Details

Origin ID

C34085;

UMLS CUI

C0255156;

OMIM relation
- Protein phosphatase 2, regulatory subunit b-prime [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- PTPA protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Isomerase Gene [NCIt concept]
- PTPA Gene [NCIt concept]
- Regulatory Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Insulin Resistance Pathway [NCIt concept]
- PLK1 Signaling Pathway [NCIt concept]
- p53 Pathway for Transcriptional Regulation [NCIt concept]
gene_product_is_physical_part_of
- Protein Phosphatase 2A [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Protein Folding [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients