2-5A-Dependent Ribonuclease

Preferred Label : 2-5A-Dependent Ribonuclease;

NCIt synonyms : Ribonuclease 4; Ribonuclease L; EC 3.1.26.-; 2-5A-Dependent RNase; Interferon-Induced 2-5A-Dependent RNase; RNase L; RNASEL;

NCIt definition : 2-5A-dependent ribonuclease (741 aa, 84 kDa) is encoded by the human RNASEL gene. This protein plays a role in both RNA processing and the antiviral response.;

Details

Origin ID

C101337;

UMLS CUI

C1568493;

Automatic exact mappings (from CISMeF team)
- Ribonuclease L [OMIM gene]
- ribonuclease 4 [MeSH concept]
- ribonuclease 4 [MeSH Supplementary Concept]
- ribonuclease L [ORDO Gene]
- ribonuclease L [HGNC gene]
Currated CISMeF NLP mapping
- 2-5A-dependent ribonuclease [MeSH Supplementary Concept]
- 2-5A-dependent ribonuclease [MeSH concept]
OMIM relation
- Ribonuclease L [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- 2-5A-dependent ribonuclease [MeSH Supplementary Concept]
- 2-5A-dependent ribonuclease [MeSH concept]
- RNASEL protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Endoribonuclease Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- RNASEL Gene [NCIt concept]
- Ribonuclease Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Ankyrin Repeat [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

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