Aldo-Keto Reductase Family 1 Member C2

Preferred Label : Aldo-Keto Reductase Family 1 Member C2;

NCIt synonyms : Type III 3-Alpha-Hydroxysteroid Dehydrogenase; Type II Dihydrodiol Dehydrogenase; Dihydrodiol Dehydrogenase 2; Chlordecone Reductase Homolog HAKRD; Dihydrodiol Dehydrogenase/Bile Acid-Binding Protein; Aldo-Keto Reductase Family 1, Member C2 (Dihydrodiol Dehydrogenase 2; Bile Acid Binding Protein; 3-Alpha Hydroxysteroid Dehydrogenase, Type III); Pseudo-Chlordecone Reductase; EC 1.3.1.20; AKR1C-Pseudo; 3-Alpha-HSD3; EC 1.1.1.213; Trans-1,2-Dihydrobenzene-1,2-Diol Dehydrogenase; AKR1C2;

NCIt definition : Aldo-keto reductase family 1 member C2 (323 aa, 37 kDa) is encoded by the human AKR1C2 gene. This protein plays a role in the metabolism of steroid hormones and the inactivation of androgens.;

Details

Origin ID

C105428;

UMLS CUI

C1456345;

OMIM relation
- Aldo-keto reductase family 1, member c2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- AKR1C2 protein, human [MeSH Supplementary Concept]
- AKR1C2 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- AKR1C2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Adrenal Gland [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Steroid Hormone Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Steroid Metabolic Process [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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