Exosome Complex Exonuclease RRP44

Preferred Label : Exosome Complex Exonuclease RRP44;

NCIt synonyms : EC 3.1.26.-; EC 3.1.13.-; Protein DIS3 Homolog; Ribosomal RNA-Processing Protein 44; DIS3; Mitotic Control Protein Dis3 Homolog; Exosome Component 11; EXOSC11;

NCIt definition : Exosome complex exonuclease RRP44 (958 aa, 109 kDa) is encoded by the human DIS3 gene. This protein is involved in the mediation of rRNA processing.;

NCIt note : Exosome complex exonuclease RRP44 has both 3'-5' exonuclease and endonuclease activities. (UniProt);

Details

Origin ID

C96360;

UMLS CUI

C2935975;

OMIM relation
- Dis3 homolog, exosome endoribonuclease and 3-prime-5-prime exoribonuclease [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- DIS3 protein, human [MeSH Supplementary Concept]
- DIS3 protein, human [MeSH concept]
gene_encodes_gene_product
- DIS3 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Ribonuclease Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- 3'-5' Exonuclease [NCIt concept]
- Hydrolase [NCIt concept]
- RNA Binding Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- RNA Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- RNA Degradation [NCIt concept]
- RNA Processing [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients