Histone-Arginine Methyltransferase CARM1

Preferred Label : Histone-Arginine Methyltransferase CARM1;

NCIt synonyms : Protein Arginine N-Methyltransferase 4; Coactivator-Associated Arginine Methyltransferase 1; EC 2.1.1.125;

NCIt definition : Histone-arginine methyltransferase CARM1 (585 aa, 63 kDa) is encoded by the human CARM1 gene. This protein is involved in the mediation of protein methylation that, in turn, regulates both chromatin organization and transcription.;

Details

Origin ID

C88223;

UMLS CUI

C4282330;

Currated CISMeF NLP mapping
- coactivator-associated arginine methyltransferase 1 [MeSH concept]
- coactivator-associated arginine methyltransferase 1 [MeSH Supplementary Concept]
OMIM relation
- Coactivator-associated arginine methyltransferase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- CARM1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- CARM1 Transcription Regulation Pathway [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Estrogen Receptor Regulation by CARM1 Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- High Grade Prostatic Intraepithelial Neoplasia [NCIt concept]
- Prostate Adenocarcinoma [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Gene Expression [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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