" /> High Grade Prostatic Intraepithelial Neoplasia - CISMeF





Preferred Label : High Grade Prostatic Intraepithelial Neoplasia;

NCIt synonyms : High-Grade Intraepithelial Neoplasia of the Prostate; High-Grade Intraepithelial Neoplasia of Prostate; High-Grade PIN; HGPIN; High-Grade Prostatic Intraepithelial Neoplasia;

NCIt related terms : High-grade Prostatic Intraepithelial Neoplasia (PIN); Prostatic intraepithelial neoplasia (high grade);

NCIt definition : Prostatic intraepithelial neoplasia characterized by the presence of morphologically malignant cells lining the acini and ducts. The malignant cells are enlarged, contain prominent nucleoli, and have increased nuclear/cytoplasmic ratio. The malignant cells may grow within the ducts and acini in four architectural patterns: flat, tufting, micropapillary, and cribriform. The presence of high grade prostatic intraepithelial neoplasia in needle biopsy is a risk factor for the subsequent detection of carcinoma on repeat biopsy.;

Neoplastic status : Undetermined;

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09/07/2025


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