CARM1 wt Allele

Preferred Label : CARM1 wt Allele;

NCIt synonyms : Coactivator-Associated Arginine Methyltransferase 1 wt Allele; PRMT4;

NCIt definition : Human CARM1 wild-type allele is located in the vicinity of 19p13.2 and is approximately 51 kb in length. This allele, which encodes histone-arginine methyltransferase CARM1 protein, plays a role in transcription regulation, protein methylation and chromatin remodeling. Aberrant expression of the gene is associated with both prostate adenocarcinomas and high-grade prostatic intraepithelial neoplasia.;

GenBank Accession Number : AF055027;

Details

Origin ID

C88222;

UMLS CUI

C2981747;

OMIM relation
- Coactivator-associated arginine methyltransferase 1 [OMIM gene]
Semantic type(s)
- Gene or Genome [UMLS semantic type]
gene_associated_with_disease
- High Grade Prostatic Intraepithelial Neoplasia [NCIt concept]
- Prostate Adenocarcinoma [NCIt concept]
gene_found_in_organism
- Human [NCIt concept]
gene_in_chromosomal_location
- 19p13.2 [NCIt concept]
gene_is_element_in_pathway
- Androgen Receptor Regulation Pathway [NCIt concept]
- CARM1 Transcription Regulation Pathway [NCIt concept]
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
- ERBB2 Signaling Pathway [NCIt concept]
- Estrogen Receptor Regulation by CARM1 Pathway [NCIt concept]
- Gene Expression Regulation by Vitamin D Receptor Pathway [NCIt concept]
- p53 Effector Pathway [NCIt concept]
gene_plays_role_in_process
- Chromatin Remodeling [NCIt concept]
- Gene Expression [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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