Interferon-Induced Helicase C Domain-Containing Protein 1

Preferred Label : Interferon-Induced Helicase C Domain-Containing Protein 1;

NCIt synonyms : RNA Helicase-DEAD Box Protein 116; Helicase with 2 CARD Domains; EC 3.6.4.13; MDA-5; Murabutide Down-Regulated Protein; Clinically Amyopathic Dermatomyositis Autoantigen 140 kDa; Interferon-Induced With Helicase C Domain Protein 1; RLR-2; Melanoma Differentiation-Associated Protein 5; CADM-140 Autoantigen; Melanoma Differentiation Associated Protein-5; Helicard; IFIH1;

NCIt definition : Interferon-induced helicase C domain-containing protein 1 (1025 aa, 117 kDa) is encoded by the human IFIH1 gene. This protein is involved in the positive regulation of antiviral responses.;

Details

Origin ID

C119721;

UMLS CUI

C1310463;

Automatic exact mappings (from CISMeF team)
- Interferon-Induced Helicase, IFIH1 [MeSH Descriptor]
- Interferon-induced helicase C domain-containing protein 1 [OMIM gene]
- MDA5 [LOINC component]
- interferon induced with helicase C domain 1 [ORDO Gene]
- interferon induced with helicase C domain 1 [HGNC gene]
OMIM relation
- Interferon-induced helicase C domain-containing protein 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- IFIH1 protein, human [MeSH Supplementary Concept]
- IFIH1 protein, human [MeSH concept]
concept_is_in_subset
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Helicase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- IFIH1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- ATPase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- RIG-I-Like Receptor Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- ATP Hydrolysis [NCIt concept]
- Antiviral Response [NCIt concept]
- Hydrolysis [NCIt concept]
- Interferon Signaling Process [NCIt concept]
- Nucleic Acid Binding [NCIt concept]
- RNA Binding [NCIt concept]
- RNA Processing [NCIt concept]
- Translation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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