Interferon-Induced Helicase, IFIH1

Preferred Label : Interferon-Induced Helicase, IFIH1;

MeSH definition : A DEAD box RNA helicase that contains two N-terminal CASPASE ACTIVATION AND RECRUITMENT DOMAINS. It functions as a sensor of viral NUCLEIC ACIDS such as DOUBLE-STRANDED RNA and activates the INNATE IMMUNE RESPONSE by inducing the expression of INTERFERON-ALPHA and INTERFERON-BETA. It may also regulate cell growth and APOPTOSIS.;

MeSH synonym : Helicase, IFIH1 Interferon-Induced; IFIH1 Interferon-Induced Helicase; Interferon Induced Helicase, IFIH1; Helicard; Melanoma Differentiation-Associated Protein 5; Melanoma Differentiation Associated Protein 5; CADM-140 Autoantigen; Autoantigen, CADM-140; CADM 140 Autoantigen; Interferon Induced with Helicase C Domain 1; Interferon-Induced Helicase C Domain-Containing Protein 1; Interferon Induced Helicase C Domain Containing Protein 1; IFIH1 Protein;

Registry Number MeSH : EC 3.6.4.13;

UNII : EC 3.6.4.13;

Details

Origin ID

D000072640;

UMLS CUI

C4255437;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- contraindications [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Automatic exact mappings (from CISMeF team)
- Interferon-Induced Helicase C Domain-Containing Protein 1 [NCIt concept]
- Interferon-induced helicase C domain-containing protein 1 [OMIM gene]
- interferon induced with helicase C domain 1 [ORDO Gene]
- interferon induced with helicase C domain 1 [HGNC gene]
Record concept(s)
- Interferon-Induced Helicase, IFIH1 [MeSH concept]
Related MeSH Supplementary Concept(s)
- IFIH1 protein, human [MeSH Supplementary Concept]
- Ifih1 protein, mouse [MeSH Supplementary Concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]

Keyword's position in hierarchy(ies) :

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