Lysine-Specific Demethylase 4C

Preferred Label : Lysine-Specific Demethylase 4C;

NCIt synonyms : [Histone H3]-Trimethyl-L-Lysine(9) Demethylase 4C; GASC-1 Protein; Jumonji Domain-Containing Protein 2C; JmjC Domain-Containing Histone Demethylation Protein 3C; KDM4C; Lysine Demethylase 4C; Gene Amplified In Squamous Cell Carcinoma 1 Protein; EC 1.14.11.-; Lysine (K)-Specific Demethylase 4C;

NCIt definition : Lysine-specific demethylase 4C (1056 aa, 120 kDa) is encoded by the human KDM4C gene. This protein is involved in the demethylation of trimethylated lysine-9 and -36 in histone H3.;

NCI Metathesaurus CUI : CL550952;

Details

Origin ID

C148358;

UMLS CUI

C1439201;

Automatic exact mappings (from CISMeF team)
- Lysine demethylase 4c [OMIM gene]
- lysine demethylase 4C [HGNC gene]
OMIM relation
- Lysine demethylase 4c [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- KDM4C protein, human [MeSH Supplementary Concept]
- KDM4C protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KDM4C Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_structural_domain_or_motif
- PHD Finger [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Coregulation Pathway for Androgen Receptor Activity [NCIt concept]
gene_product_plays_role_in_biological_process
- Histone Demethylation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Stimulation of Cell Proliferation [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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