Uroporphyrinogen-III Synthase

Preferred Label : Uroporphyrinogen-III Synthase;

NCIt synonyms : Uroporphyrinogen-III Cosynthase; EC 4.2.1.75; Hydroxymethylbilane Hydrolyase; Uroporphyrinogen III Synthase; Hydroxymethylbilane Hydrolyase [Cyclizing]; UROIIIS; UROS;

NCIt definition : Uroporphyrinogen-III synthase (265 aa, 29 kDa) is encoded by the human UROS gene. This protein plays a role in cyclization of hydroxymethylbilane yielding the macrocyclic porphyrin precursor uroporphyrinogen III.;

Details

Origin ID

C213528;

OMIM relation
- Uroporphyrinogen III synthase [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
- UROS Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Porphyrin and Chlorophyll Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Biosynthetic Process [NCIt concept]

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