Nitric Oxide Synthase, Endothelial

Preferred Label : Nitric Oxide Synthase, Endothelial;

NCIt synonyms : Nitric Oxide Synthase-3; Endothelial Nitric Oxide Synthase; NOS Type III; Endothelial Nitric Oxide Synthase 3; ECNOS; Endothelial NOS; NOS3; NOSIII; Constitutive NOS; cNOS; EC 1.14.13.39; EC-NOS; eNOS; Nitric Oxide Synthase 3;

NCIt definition : Nitric oxide synthase, endothelial (1203 aa, 133 kDa) is encoded by the human NOS3 gene. This protein plays a role in the modulation of vascular smooth muscle relaxation, VEGF-induced angiogenesis and blood coagulation.;

Details

Origin ID

C38571;

UMLS CUI

C0669365;

Currated CISMeF NLP mapping
- Nitric oxide synthase 3 [OMIM Phenotype]
- enoses [IUPAC Term]
OMIM relation
- Nitric oxide synthase 3 [OMIM Phenotype]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NOS3 protein, human [MeSH concept]
- NOS3 protein, human [MeSH Supplementary Concept]
- enoses [IUPAC Term]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- NOS3 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Angiogenesis Pathway [NCIt concept]
- Angiopoietin-1 Receptor Signaling Pathway [NCIt concept]
- Arginine and Proline Metabolism Pathway [NCIt concept]
- Calcium-Mediated Signaling Pathway [NCIt concept]
- Corticosteroid Cardioprotection Pathway [NCIt concept]
- Hypoxia-Inducible Factor Pathway [NCIt concept]
- Ion Channels in Vascular Endothelium Pathway [NCIt concept]
- Nitric Oxide Pathway [NCIt concept]
- Plasma Membrane Estrogen Receptor Signaling Pathway [NCIt concept]
- Thromboxane A2 Receptor Family Signaling Pathway [NCIt concept]
- VEGF Signaling Pathway [NCIt concept]
- VEGFR1 Signaling Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Angiogenic Process [NCIt concept]
- Intercellular Communication Process [NCIt concept]
- Muscle Contraction [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Platelet Aggregation Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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