NADP-Dependent Malic Enzyme

Preferred Label : NADP-Dependent Malic Enzyme;

NCIt synonyms : Malate Dehydrogenase; Pyruvic-Malic Carboxylase; EC 1.1.1.40; Malic Enzyme 1; NADP-ME; ME1;

NCIt definition : NADP-dependent malic enzyme (572 aa, 64 kDa) is encoded by the human ME1 gene. This protein plays a role in the oxidative decarboxylation of malate.;

NCI Metathesaurus CUI : CL509805;

Details

Origin ID

C127141;

UMLS CUI

C4283949;

Automatic exact mappings (from CISMeF team)
- Malate dehydrogenase [LOINC component]
- Malate dehydrogenase (oxaloacetate-decarboxylating) (substance) [SNOMED CT concept]
- Malate dehydrogenase (substance) [SNOMED CT concept]
- Malic enzyme 1 [OMIM gene]
- malate dehydrogenase [MeSH Descriptor]
- malate dehydrogenase [MeSH concept]
- malate dehydrogenase [EMDN type]
- malate dehydrogenase (decarboxylating) [MeSH Supplementary Concept]
- malic enzyme 1 [HGNC gene]
OMIM relation
- Malic enzyme 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- ME1 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_biochemical_function
- Malate Dehydrogenase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Acetyl Group Shuttle Pathway [NCIt concept]
- PPAR Signaling Pathway [NCIt concept]
- PPAR-alpha Gene Regulation Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Lipid Metabolic Process [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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