E3 Ubiquitin-Protein Ligase UBR5

Preferred Label : E3 Ubiquitin-Protein Ligase UBR5;

NCIt synonyms : EC 6.3.2.-, Formerly; Hyperplastic Discs Protein Homolog; Progestin-Induced Protein; E3 Identified By Differential Display; E3 Ubiquitin-Protein Ligase, HECT Domain-Containing 1; Progestin Induced Protein; hHYD; EC 2.3.2.26; HECT-Type E3 Ubiquitin Transferase UBR5; UBR5;

NCIt definition : E3 ubiquitin-protein ligase UBR5 (2799 aa, 309 kDa) is encoded by the human UBR5 gene. This protein plays a role in the promotion of both protein ubiquitination and protein catabolism.;

Details

Origin ID

C111930;

UMLS CUI

C0965793;

Automatic exact mappings (from CISMeF team)
- Ubiquitin-protein ligase e3 component n-recognin 5 [OMIM gene]
OMIM relation
- Ubiquitin-protein ligase e3 component n-recognin 5 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- UBR5 protein, human [MeSH Supplementary Concept]
- UBR5 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- UBR5 Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Ubiquitin-mediated Proteolysis Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Proliferation Regulatory Process [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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