Endonuclease 8-Like 1

Preferred Label : Endonuclease 8-Like 1;

NCIt synonyms : Endonuclease VIII-Like 1; FPG1; DNA Glycosylase/AP Lyase Neil1; EC 3.2.2.-; EC 4.2.99.18; Nei Homolog 1; DNA-(Apurinic Or Apyrimidinic Site) Lyase Neil1; NEH1; Endonuclease VIII; NEIL1;

NCIt definition : Endonuclease 8-like 1 (390 aa, 44 kDa) is encoded by the human NEIL1 gene. This protein plays a role in base excision-based repair of DNA.;

NCIt note : Endonuclease 8-like 1 has both glycosidase (nucleotidase) and DNA lyase activity.;

Détails

Origin ID

C124097;

UMLS CUI

C1122828;

Automatic exact mappings (from CISMeF team)
- Nei-like dna glycosylase 1 [OMIM gene]
- deoxyribonuclease (pyrimidine dimer) [MeSH Descriptor]
- endonuclease VIII [MeSH concept]
OMIM relation
- Nei-like dna glycosylase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- NEIL1 protein, human [MeSH Supplementary Concept]
- NEIL1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Lyase Gene [NCIt concept]
- NEIL1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Centrosome [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Binding Protein [NCIt concept]
- DNA Repair Endonuclease [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Base Excision Repair [NCIt concept]
- DNA Binding [NCIt concept]
- DNA Repair [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients