DNA Repair Endonuclease

Preferred Label : DNA Repair Endonuclease;

NCIt definition : DNA Repair Endonucleases specifically catalyze the hydrolysis of interior DNA phosphodiester bonds during correction of errors in DNA structure and sequence to protect genetic information against chemical, radiation or spontaneous damage and against replication errors, and to restore DNA to its original state.;

Details

Origin ID

C21438;

UMLS CUI

C1333236;

Biochemical function of gene products
- 40S Ribosomal Protein S3 [NCIt concept]
- Crossover Junction Endonuclease MUS81 [NCIt concept]
- DNA Annealing Helicase and Endonuclease ZRANB3 [NCIt concept]
- DNA Endonuclease RBBP8 [NCIt concept]
- DNA Excision Repair Protein ERCC-1 [NCIt concept]
- DNA Repair Endonuclease XPF [NCIt concept]
- DNA Repair Protein Complementing XP-G Cells [NCIt concept]
- DNA Replication ATP-Dependent Helicase/Nuclease DNA2 [NCIt concept]
- DNA-(Apurinic or Apyrimidinic Site) Lyase 2 [NCIt concept]
- Endonuclease 8-Like 1 [NCIt concept]
- Endonuclease 8-Like 3 [NCIt concept]
- Endonuclease III-Like Protein 1 [NCIt concept]
- Flap Endonuclease 1 [NCIt concept]
- Flap Endonuclease GEN Homolog 1 [NCIt concept]
- Methyl-CpG-Binding Domain Protein 4 [NCIt concept]
- Mismatch Repair Endonuclease PMS2 [NCIt concept]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Hydrolysis [NCIt concept]

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