DNA-(Apurinic or Apyrimidinic Site) Lyase 2

Preferred Label : DNA-(Apurinic or Apyrimidinic Site) Lyase 2;

NCIt synonyms : Apurinic/Apyrimidinic Endonuclease-Like 2; APEXL2; APEX Nuclease-Like 2; Apurinic-Apyrimidinic Endonuclease 2; AP Endonuclease XTH2; EC 3.1.-.-; AP Endonuclease 2; APEX Nuclease 2; EC 4.2.99.18; Apurinic/Apyrimidinic Endonuclease 2; Apurinic-Apyrimidinic Endonuclease-2; APEX2;

NCIt definition : DNA-(apurinic or apyrimidinic site) lyase 2 (518 aa, 57 kDa) is encoded by the human APEX2 gene. This protein is involved in DNA repair.;

Details

Origin ID

C21423;

UMLS CUI

C1506647;

OMIM relation
- Apex nuclease (apurinic/apyrimidinic endonuclease) 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- APEX2 protein, human [MeSH concept]
- APEX2 protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- APEX2 Gene [NCIt concept]
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Lyase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrion [NCIt concept]
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Repair Endonuclease [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Base Excision Repair Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Base Excision Repair [NCIt concept]
- DNA Repair [NCIt concept]
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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