Flap Endonuclease GEN Homolog 1

Preferred Label : Flap Endonuclease GEN Homolog 1;

NCIt synonyms : GEN1 Holliday Junction 5 Flap Endonuclease; Gen Endonuclease Homolog 1; EC 3.1.-.-; Holliday Junction Resolvase; GEN1;

NCIt definition : Flap endonuclease GEN homolog 1 (908 aa, 103 kDa) is encoded by the human GEN1 gene. This protein plays a role in homologous recombination and DNA repair.;

Details

Origin ID

C124103;

UMLS CUI

C2606719;

Automatic exact mappings (from CISMeF team)
- GEN1 Holliday junction 5' flap endonuclease [HGNC gene]
- Gen1 holliday junction 5-prime flap endonuclease [OMIM gene]
- holliday junction resolvases [MeSH Descriptor]
- holliday junction resolvases [MeSH concept]
OMIM relation
- Gen1 holliday junction 5-prime flap endonuclease [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- GEN1 protein, human [MeSH Supplementary Concept]
- GEN1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- GEN1 Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Repair Endonuclease [NCIt concept]
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Double Strand Break Repair [NCIt concept]
- Homologous Recombination [NCIt concept]
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients