DNA Repair Endonuclease XPF

Preferred Label : DNA Repair Endonuclease XPF;

NCIt synonyms : XPF; ERCC4; RAD1; EC 3.1.-.; DNA Excision Repair Protein-ERCC4; Xeroderma Pigmentosum Group F-Complementing Protein; DNA Excision Repair Protein ERCC-4; DNA Repair Protein Complementing XP-F Cells; Xeroderma Pigmentosum, Complementation Group F;

NCIt definition : DNA repair endonuclease XPF (916 aa, 104 kDa) is encoded by the human ERCC4 gene. This protein is involved in DNA double strand break and nucleotide excision repair.;

Details

Origin ID

C21459;

UMLS CUI

C1568501;

OMIM relation
- Ercc excision repair 4, endonuclease catalytic subunit [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ERCC4 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNA Repair Gene [NCIt concept]
- ERCC4 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_biochemical_function
- DNA Repair Endonuclease [NCIt concept]
- Fanconi Anemia Complementation Group Protein [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_is_element_in_pathway
- Nucleotide Excision Repair Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Xeroderma Pigmentosum, Complementation Group F [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- Nucleotide Excision Repair [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients