E3 Ubiquitin-Protein Ligase TRIM21

Preferred Label : E3 Ubiquitin-Protein Ligase TRIM21;

NCIt synonyms : SS-A; Sjoegren Syndrome Type A Antigen; RING Finger Protein 81; Ro(SS-A); Tripartite Motif-Containing Protein 21; 52 kDa Ribonucleoprotein Autoantigen Ro/SS-A; EC 6.3.2.-, Formerly; 52 kDa Ro Protein; EC 2.3.2.27;

NCIt definition : E3 ubiquitin-protein ligase TRIM21 (475 aa, 54 kDa) is encoded by the human TRIM21 gene. This protein is involved in both the mediation of protein ubiquitination and the regulation of the cell cycle.;

Details

Origin ID

C94755;

UMLS CUI

C1722829;

OMIM relation
- Tripartite motif-containing protein 21 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TRIM21 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- TRIM21 Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- Ubiquitin-Transferase Gene [NCIt concept]
gene_product_has_biochemical_function
- Ubiquitination Regulation Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Coiled-Coil Domain [NCIt concept]
- Ring Finger Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
- TRIM Motif [NCIt concept]
gene_product_is_element_in_pathway
- Systemic Lupus Erythematosus Pathway [NCIt concept]
gene_product_is_physical_part_of
- Ubiquitin Protein Ligase [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Cycle Regulation Process [NCIt concept]
- Ubiquitinated Protein Degradation [NCIt concept]
- Ubiquitination [NCIt concept]

Keyword's position in hierarchy(ies) :

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