Tyrosinase - CISMeF

Preferred Label : Tyrosinase;

NCIt synonyms : TYR; SK29-AB; LB24-AB; Monophenol Monooxygenase; EC 1.14.18.1; Tumor Rejection Antigen AB;

NCIt definition : Tyrosinase (529 aa, 60 kDa) is encoded by the human TYR gene. This protein is involved in pigment biosynthesis, eye development and the metabolism of both tyrosine and L-dopa.;

Details

Origin ID

C17226;

UMLS CUI

C4048300;

Currated CISMeF NLP mapping
- Monophenol monooxygenase (substance) [SNOMED CT concept]
- monophenol monooxygenase [MeSH Descriptor]
- monophenol monooxygenase [MeSH concept]
- monophenol monooxygenase [SNOMED Notion]
OMIM relation
- Tyrosinase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TYR Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Tumor Marker [NCIt concept]
gene_product_is_element_in_pathway
- Melanogenesis Pathway [NCIt concept]
- Riboflavin Metabolism Pathway [NCIt concept]
- Tyrosine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Melanogenesis [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
is_target
- Adenovirus Encoding Tyrosinase/MART-1/MAGEA6-transduced Autologous Dendritic Cell Vaccine [NCIt concept]
- HLA-B44-Restricted Tyrosinase Peptide [NCIt concept]
- Immunotherapy Regimen MKC-1106-MT [NCIt concept]
- Long Peptide Vaccine 7 [NCIt concept]
- Recombinant Fowlpox-Tyrosinase Vaccine [NCIt concept]
- TIL 1383I T Cell Receptor-Transduced Autologous T Cells [NCIt concept]
- Tetravalent RNA-lipoplex Cancer Vaccine BNT111 [NCIt concept]
- Tyrosinase Peptide [NCIt concept]
- Tyrosinase:146-156 Peptide [NCIt concept]
- Tyrosinase:206-214 Peptide [NCIt concept]
- Tyrosinase:240-251(244S) Peptide [NCIt concept]
- Tyrosinase:368-376(370D) Peptide [NCIt concept]
- Vaccinia-Tyrosinase Vaccine [NCIt concept]

Keyword's position in hierarchy(ies) :

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