Tyrosinase:240-251(244S) Peptide

Preferred Label : Tyrosinase:240-251(244S) Peptide;

NCIt synonyms : Tyrosinase:240-251(244S); Tyrosinase 240-251 244S;

NCIt definition : A recombinant peptide consisting of amino acid residues 240 to 251 of the enzyme tyrosinase, a protein frequently expressed by melanoma cells, with serine substitution at position 244 to improve immunogenicity. Vaccination with tyrosinase:240-251(244S) may stimulate the host immune response to mount a cytotoxic T lymphocyte (CTL) response against tyrosinase-expressing tumor cells.;

NSC code : 699049;

Details

Origin ID

C2819;

UMLS CUI

C1519722;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
has_target
- Tyrosinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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