NCIt definition : A synthetic peptide consisting of amino acids 368 through 376 of the melanoma-associated
antigen tyrosinase with an amino acid aspartic acid at position 370 to improve immunogenicity.
Vaccination with TYROSINASE:368-376(370D) may stimulate the host immune system to
mount a cytotoxic T lymphocyte (CTL) response against tumor cells positive for tyrosinase,
thereby decreasing tumor growth.;