HLA-B44-Restricted Tyrosinase Peptide

Preferred Label : HLA-B44-Restricted Tyrosinase Peptide;

NCIt definition : A synthetic peptide consisting of synthetic human leukocyte antigen (HLA)-B44-binding peptides derived from amino acid sequences of the melanoma-associated enzyme tyrosinase with potential antitumor activity. Vaccination with HLA-B44-restricted tyrosinase peptide may stimulate cytotoxic T lymphocyte response against tyrosinase-expressing tumor cells, resulting in decreased tumor growth and cell lysis.;

NSC code : 731580;

Details

Origin ID

C48634;

UMLS CUI

C1708278;

Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Immunologic Factor [UMLS semantic type]
- Pharmacologic Substance [UMLS semantic type]
chemical_or_drug_affects_cell_type_or_tissue
- Cytotoxic T-Lymphocyte [NCIt concept]
chemical_or_drug_has_mechanism_of_action
- Antigen Sensitization [NCIt concept]
chemical_or_drug_has_physiologic_effect
- Immunopotentiation [NCIt concept]
- T-Cell Activation [NCIt concept]
concept_is_in_subset
- NCIt Antineoplastic Agent Terminology [NCIt concept]
has_target
- Tyrosinase [NCIt concept]

Keyword's position in hierarchy(ies) :

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