Serine/Threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit

Preferred Label : Serine/Threonine-Protein Phosphatase PP1-Alpha Catalytic Subunit;

NCIt synonyms : PPP1A; PPP1CA; Serine/Threonine Protein Phosphatase PP1-Alpha 1 Catalytic Subunit; PP-1A; Protein Phosphatase 1 Catalytic Subunit Alpha; EC 3.1.3.16; Protein Phosphatase-1 Catalytic Subunit Alpha;

NCIt definition : Serine/threonine-protein phosphatase PP1-alpha catalytic subunit (330 aa, 38 kDa) is encoded by the human PPP1CA gene. This protein is involved in protein dephosphorylation, glycogen metabolism and cell division.;

NCIt note : Protein_Plays_Role_In_Biological_Process: Ionic Conductance Regulation, Synaptic Plasticity, Memory, Metabolic Regulation;

Détails

Origin ID

C34079;

UMLS CUI

C1335536;

OMIM relation
- Protein phosphatase 1, catalytic subunit, alpha isoform [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- PPP1CA protein, human [MeSH concept]
- PPP1CA protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- PPP1CA Gene [NCIt concept]
- Phosphatase Family Gene [NCIt concept]
- Protein Phosphatase Gene [NCIt concept]
- Protein Serine/Threonine Phosphatase Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
- Protein Complex Subunit [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Actin Cytoskeleton Regulation Pathway [NCIt concept]
- BMP Receptor Signaling Pathway [NCIt concept]
- CK1/CDK5 Regulation Pathway [NCIt concept]
- Centrosome Pathway [NCIt concept]
- Focal Adhesion Pathway [NCIt concept]
- Hippo Signaling Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Long-Term Potentiation Pathway [NCIt concept]
- Oocyte Meiosis Pathway [NCIt concept]
- TGF-Beta Receptor Signaling Pathway [NCIt concept]
- Vascular Smooth Muscle Contraction Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Division Process [NCIt concept]
- Dephosphorylation [NCIt concept]
- Hydrolysis [NCIt concept]
- Protein Dephosphorylation [NCIt concept]
- Protein Synthesis [NCIt concept]
- Signal Transduction [NCIt concept]

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