Acyl-Protein Thioesterase 1

Preferred Label : Acyl-Protein Thioesterase 1;

NCIt synonyms : Lysophospholipid-Specific Lysophospholipase; LysoPLA I; EC 3.1.2.-; Lysophospholipase I; Acyl-protein Thioesterase-1; LYPLA1;

NCIt definition : Acyl-protein thioesterase 1 (230 aa, 25 kDa) is encoded by the human LYPLA1 gene. This protein plays a role in regulating membrane lysophospholipid levels.;

NCIt note : Elevated levels of lysophospholipids are associated with atherosclerosis and hyperlipidemia.;

Details

Origin ID

C104626;

UMLS CUI

C3539734;

OMIM relation
- Lysophospholipase I [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- LYPLA1 Gene [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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