Tryptophan-tRNA Ligase, Mitochondrial

Preferred Label : Tryptophan-tRNA Ligase, Mitochondrial;

NCIt synonyms : Tryptophanyl-tRNA Synthetase; TrpRS; Tryptophan--tRNA Ligase, Mitochondrial; (Mt)TrpRS; EC 6.1.1.2; Mitochondrial TrpRS; Tryptophanyl-tRNA Synthetase 2; Tryptophanyl-tRNA Synthetase, Mitochondrial; WARS2; Tryptophan tRNA Ligase 2, Mitochondrial;

NCIt definition : Tryptophan-tRNA ligase, mitochondrial (360 aa, 110 kDa) is encoded by the human WARS2 gene. This protein is involved in the synthesis of tryptophyl-tRNA.;

NCI Metathesaurus CUI : CL521338;

Details

Origin ID

C132154;

UMLS CUI

C4321259;

Automatic exact mappings (from CISMeF team)
- Tryptophan-tRNA ligase [MeSH Descriptor]
- Tryptophan-transfer ribonucleic acid ligase (substance) [SNOMED CT concept]
- Tryptophanyl-trna synthetase 1 [OMIM gene]
- Tryptophanyl-trna synthetase 2 [OMIM gene]
- tryptophanyl tRNA synthetase 2, mitochondrial [ORDO Gene]
OMIM relation
- Tryptophanyl-trna synthetase 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
- WARS2 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_chemical_classification
- Aminoacyl-tRNA Ligase Family [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Aminoacyl-tRNA Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- RNA Processing [NCIt concept]
- Translational Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

You can consult :

recommendations
documents concerning education
documents for patients