Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3

Preferred Label : Ectonucleotide Pyrophosphatase/Phosphodiesterase Family Member 3;

NCIt synonyms : Phosphodiesterase I/Nucleotide Pyrophosphatase 3; CD203c; Phosphodiesterase-I Beta; E-NPP 3; CD203c Antigen; PD-Ibeta; Phosphodiesterase I Beta; ENPP3;

NCIt definition : Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 (875 aa, 100 kDa) is encoded by the human ENPP3 gene. This protein plays a role in the cleavage of phosphodiester and phosphosulfate bonds.;

NCIt note : Ectonucleotide pyrophosphatase/phosphodiesterase family member 3 has the following functionalities: alkaline phosphodiesterase I (EC:3.1.4.1) and nucleotide pyrophosphatase (EC:3.6.1.9; NPPase; nucleotide diphosphatase). (UniProt);

Details

Origin ID

C147048;

UMLS CUI

C1447996;

Automatic exact mappings (from CISMeF team)
- Ectonucleotide pyrophosphatase/phosphodiesterase 3 [OMIM gene]
OMIM relation
- Ectonucleotide pyrophosphatase/phosphodiesterase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ENPP3 protein, human [MeSH Supplementary Concept]
- ENPP3 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ENPP3 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Esterase Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Nicotinate and Nicotinamide Metabolism Pathway [NCIt concept]
- Pantothenate and CoA Biosynthesis Pathway [NCIt concept]
- Purine Metabolism Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
- Riboflavin Metabolism Pathway [NCIt concept]
- Starch and Sucrose Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Nucleotide Metabolic Process [NCIt concept]
is_target
- Anti-AGS-16 Monoclonal Antibody AGS-16M18 [NCIt concept]
- Anti-ENPP3 Antibody-Drug Conjugate AGS-16C3F [NCIt concept]
- Anti-ENPP3/Anti-CD3 Bispecific Antibody XmAb819 [NCIt concept]
- Anti-ENPP3/MMAF Antibody-Drug Conjugate AGS-16M8F [NCIt concept]

Keyword's position in hierarchy(ies) :

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