Chitotriosidase-1

Preferred Label : Chitotriosidase-1;

NCIt synonyms : Methylumbelliferyl-Tetra-N-Acetylchitotetraoside Hydrolase; EC 3.2.1.14; Plasma Methylumbelliferyl Tetra-N-Acetylchitotetraoside Hydrolase; Chitinase-1; Chitotriosidase; CHIT1;

NCIt definition : Chitotriosidase-1 (466 aa, 52 kDa) is encoded by the human CHIT1 gene. This protein is involved in the degradation of chitins.;

NCIt note : Elevated plasma levels of chitotriosidase-1 is associated with Gaucher disease.;

Détails

Origin ID

C120053;

UMLS CUI

C3502322;

Automatic exact mappings (from CISMeF team)
- Chitinase (substance) [SNOMED CT concept]
- Chitinase 1 [OMIM gene]
- Chitotriosidase [LOINC component]
- Chitotriosidase [MedDRA Preferred Term]
- chitinase 1 [HGNC gene]
- chitotriosidase [MeSH Supplementary Concept]
- chitotriosidase [MeSH concept]
OMIM relation
- Chitinase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Chit1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CHIT1 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Macrophage [NCIt concept]
- Spleen [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
gene_product_has_biochemical_function
- Polysaccharide Hydrolase [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Amino and Nucleotide Sugars Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Antimicrobial Effect [NCIt concept]
- Catabolic Process [NCIt concept]
- Hydrolysis [NCIt concept]

Position du mot-clé dans l'(les) arborescence(s) :

Vous pouvez consulter :

recommendations
documents concerning education
documents for patients