Beta-1,3-N-Acetylglucosaminyltransferase Manic Fringe

Preferred Label : Beta-1,3-N-Acetylglucosaminyltransferase Manic Fringe;

NCIt synonyms : MFNG; Manic Fringe; EC 2.4.1.222; O-Fucosylpeptide 3-Beta-N-Acetylglucosaminyltransferase; Manic Fringe Protein;

NCIt definition : Beta-1,3-N-acetylglucosaminyltransferase manic fringe (321 aa, 36 kDa) is encoded by the human MFNG gene. This protein is involved in Notch protein fucosylation and the modulation of Notch signaling.;

Details

Origin ID

C28499;

UMLS CUI

C1334632;

Automatic exact mappings (from CISMeF team)
- Mfng o-fucosylpeptide 3-beta-n-acetylglucosaminyltransferase [OMIM gene]
OMIM relation
- Mfng o-fucosylpeptide 3-beta-n-acetylglucosaminyltransferase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Biologically Active Substance [UMLS semantic type]
UMLS correspondences (same concept)
- MFNG protein, human [MeSH concept]
- MFNG protein, human [MeSH Supplementary Concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- MFNG Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Golgi Apparatus [NCIt concept]
gene_product_has_biochemical_function
- Signaling Protein [NCIt concept]
gene_product_has_chemical_classification
- Transmembrane Protein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
- Transmembrane Domain [NCIt concept]
gene_product_is_element_in_pathway
- Notch Signaling Pathway [NCIt concept]
- O-Mannosyl Glycan Biosynthesis Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Neural Development [NCIt concept]
- Pattern Formation [NCIt concept]
- Signal Transduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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