Thioredoxin Reductase 1, Cytoplasmic

Preferred Label : Thioredoxin Reductase 1, Cytoplasmic;

NCIt synonyms : Gene Associated With Retinoic And IFN-Induced Mortality 12 Protein; Gene Associated With Retinoic And Interferon-Induced Mortality 12 Protein; Thioredoxin Reductase TR1; TR; GRIM-12; KM-102-Derived Reductase-Like Factor; Thioredoxin Reductase GRIM-12; EC 1.8.1.9; TXNRD1;

NCIt definition : Thioredoxin reductase 1, cytoplasmic (649 aa, 71 kDa) is encoded by the human TXNRD1 gene. This protein plays a role in cellular redox reactions.;

NCIt note : The functional enzyme may be comprised of a homodimer of thioredoxin reductase 1, cytoplasmic.;

Details

Origin ID

C107618;

UMLS CUI

C1872943;

Automatic exact mappings (from CISMeF team)
- Coagulation factor II receptor [OMIM gene]
- Telerehabilitation [MeSH Descriptor]
- Telomerase rna component [OMIM gene]
- Thioredoxin reductase 1 [OMIM gene]
- Transmembrane protein with egf-like and 2 follistatin-like domains 2 [OMIM gene]
- Treatment required for (contextual qualifier) (qualifier value) [SNOMED CT concept]
- Tricuspid valve insufficiency [ICD-11 Category]
- digital rectal examination [MeSH Descriptor]
- telomerase RNA component [ORDO Gene]
- thioredoxin reductase 2 [ORDO Gene]
- transplantation [MeSH Descriptor]
OMIM relation
- Thioredoxin reductase 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- TXNRD1 protein, human [MeSH Supplementary Concept]
- TXNRD1 protein, human [MeSH concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
- TXNRD1 Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Pyrimidine Metabolism Pathway [NCIt concept]
- Selenoamino Acid Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Metabolic Process [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]

Keyword's position in hierarchy(ies) :

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