Uridine 5'-Monophosphate Synthase

Preferred Label : Uridine 5'-Monophosphate Synthase;

NCIt synonyms : Orotate Phosphoribosyltransferase/Orotidine 5'-Decarboxylase; UMPS; UMP Synthase; OPRTase/OMPdecase; Uridine Monophosphate Synthetase; OPRT/ODC; Orotate Phosphoribosyltransferase/Orotidine 5'-Phosphate Decarboxylase; OPRTase/OMP Decarboxylase; OPRT/OMPD;

NCIt definition : Uridine 5'-monophosphate synthase (480 aa, 52 kDa) is encoded by the human UMPS gene. This protein plays a role in the two step conversion of orotate to uridine monophosphate.;

NCIt note : Uridine 5'-monophosphate synthase exhibits two types of enzymatic activity: orotate phosphoribosyltransferase (OPRT; EC 2.4.2.10) and orotidine-5'-monophosphate decarboxylase (ODC; EC 4.1.1.23). (UniProt);

Details

Origin ID

C190411;

UMLS CUI

C1956115;

Automatic exact mappings (from CISMeF team)
- Uridine monophosphate synthetase [LOINC component]
- Uridine monophosphate synthetase [OMIM gene]
- uridine 5'-monophosphate synthase [MeSH concept]
- uridine 5'-monophosphate synthase [MeSH Supplementary Concept]
- uridine monophosphate synthetase [ORDO Gene]
- uridine monophosphate synthetase [HGNC gene]
OMIM relation
- Uridine monophosphate synthetase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- UMPS protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Glycosyltransferase Gene [NCIt concept]
- Lyase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
- UMPS Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Non-CYP450 Enzymes Pathway [NCIt concept]
- Pyrimidine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Carbohydrate Metabolic Process [NCIt concept]
- Glycosylation [NCIt concept]
- Nucleotide Biosynthesis Process [NCIt concept]

Keyword's position in hierarchy(ies) :

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