Dihydrolipoyllysine-Residue Succinyltransferase Component of 2-Oxoglutarate Dehydrogenase Complex, Mitochondrial

Preferred Label : Dihydrolipoyllysine-Residue Succinyltransferase Component of 2-Oxoglutarate Dehydrogenase Complex, Mitochondrial;

NCIt synonyms : EC 2.3.1.61; 2-Oxoglutarate Dehydrogenase Complex Component E2; E2K; Dihydrolipoamide Succinyltransferase Component of 2-Oxoglutarate Dehydrogenase Complex; OGDC-E2; Dihydrolipoamide S-Succinyltransferase;

NCIt definition : Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial (453 aa, 49 kDa) is encoded by the human DLST gene. This protein plays a role in both the Krebs cycle and lysine catabolism.;

NCIt note : Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial is part of the 2-oxoglutarate dehydrogenase complex, which has multiple copies of 3 enzymatic components: 2-oxoglutarate dehydrogenase (E1), dihydrolipoamide succinyltransferase (E2) and lipoamide dehydrogenase (E3). (UniProt);

NCI Metathesaurus CUI : CL505083;

Details

Origin ID

C126542;

UMLS CUI

C4285067;

Automatic exact mappings (from CISMeF team)
- Dihydrolipoamide s-succinyltransferase [OMIM gene]
- dihydrolipoamide S-succinyltransferase [ORDO Gene]
- dihydrolipoamide S-succinyltransferase [HGNC gene]
- dihydrolipoamide succinyltransferase [MeSH Supplementary Concept]
OMIM relation
- Dihydrolipoamide s-succinyltransferase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
gene_encodes_gene_product
- DLST Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Mitochondrial Matrix [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Citrate Cycle (TCA Cycle) Pathway [NCIt concept]
- Lysine Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Catabolic Process [NCIt concept]
- Cell Respiration [NCIt concept]

Keyword's position in hierarchy(ies) :

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