Angiotensin-Converting Enzyme 2

Preferred Label : Angiotensin-Converting Enzyme 2;

NCIt synonyms : Angiotensin-Converting Enzyme Homolog; Metalloprotease MPROT15; ACEH; EC 3.4.17.23; ACE-Related Carboxypeptidase; Angiotensin I Converting Enzyme 2; ACE2; Angiotensin I-Converting Enzyme 2;

NCIt definition : Angiotensin-converting enzyme 2 (805 aa, 92 kDa) is encoded by the human ACE2 gene. This protein plays a role in both vasodilation and protein cleavage.;

NCIt note : Substrates for angiotensin-converting enzyme 2 include angiotensin I and angiotensin II. (UniProt);

NCI Metathesaurus CUI : CL1657365;

Details

Origin ID

C102530;

UMLS CUI

C5433525;

Currated CISMeF NLP mapping
- Angiotensin-Converting Enzyme 2 [MeSH concept]
- Angiotensin-Converting Enzyme 2 [MeSH Descriptor]
- angiotensin converting enzyme 2 [COVID-19 Thesaurus concept]
False automatic mappings
- acetone hydrazone [MeSH Supplementary Concept]
- acetone hydrazone [Substance BNPC]
OMIM relation
- Angiotensin I-converting enzyme 2 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ACE2 protein, human [MeSH Supplementary Concept]
- Angiotensin-Converting Enzyme 2 [MeSH concept]
- Angiotensin-Converting Enzyme 2 [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
- NCIt COVID-19 Clinical Terminology [NCIt concept]
- NCIt COVID-19 Terminology [NCIt concept]
gene_encodes_gene_product
- ACE2 Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Metallopeptidase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Extracellular Space [NCIt concept]
- Plasma Membrane [NCIt concept]
gene_product_has_chemical_classification
- Metalloprotein [NCIt concept]
gene_product_has_structural_domain_or_motif
- Metal Binding Site [NCIt concept]
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_biomarker_type
- Metastasis and Aggressiveness Marker [NCIt concept]
gene_product_is_element_in_pathway
- Angiotensin-converting Enzyme 2 Pathway [NCIt concept]
- Renin-Angiotensin Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Homeostatic Process [NCIt concept]
- Hydrolysis [NCIt concept]
- Metal Ion Binding [NCIt concept]
- Proteolysis [NCIt concept]
is_target
- Fluorine F 18-labeled DX600 [NCIt concept]

Keyword's position in hierarchy(ies) :

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