Preferred Label : Fluorine F 18-labeled DX600;
NCIt synonyms : 18F-DX600; Fluorine F 18-ACE2 Inhibitor DX600; 18F-labeled DX600;
NCIt definition : A radioconjugate composed of DX600, a peptide targeting angiotensin converting enzyme
2 (ACE2), labeled with the radioisotope fluorine F 18, with potential imaging activity
upon positron emission tomography (PET). Upon administration of fluorine F 18-labeled
DX600, DX600 targets and binds to ACE2. Upon PET imaging, ACE2 expression can be assessed.
ACE2 plays an important role in the renin-angiotensin system (RAS), and may be overexpressed
in tumors.;
NCI Metathesaurus CUI : CL1647842;
Origin ID : C178420;
UMLS CUI : C5555021;
Semantic type(s)
- concept_is_in_subset
- has_target
