Angiotensin-Converting Enzyme 2

Preferred Label : Angiotensin-Converting Enzyme 2;

MeSH definition : A transmembrane glycoprotein with an extracellular catalytic domain which functions as a carboxypeptidase. It cleaves a single C-terminal residue from a distinct range of substrates. The catalytic efficiency is 400-fold higher with ANGIOTENSIN II as a substrate than with ANGIOTENSIN I. Angiotensin-converting enzyme 2 is also is a functional receptor for the spike glycoprotein (SPIKE PROTEIN, CORONAVIRUS) of the CORONAVIRUSES SARS-COV, SARS-COV2, and HCOV-NL63.;

MeSH synonym : Angiotensin Converting Enzyme 2; ACE2 Protein; ACE2 Angiotensin-Converting Enzyme Protein 2; ACE2 Angiotensin Converting Enzyme Protein 2; ACE-Related Carboxypeptidase; ACE Related Carboxypeptidase; Carboxypeptidase, ACE-Related; Angiotensin-Converting Enzyme-Related Carboxypeptidase; Angiotensin Converting Enzyme Related Carboxypeptidase; Carboxypeptidase, Angiotensin-Converting Enzyme-Related; ACE2 Enzyme;

Wikipedia link : https://en.wikipedia.org/wiki/Angiotensin-converting enzyme 2;

UNII : EC 3.4.17.23;

Details

Origin ID

D000085962;

UMLS CUI

C0960880;

Allowable qualifiers
- administration and dosage [MeSH Qualifier]
- adverse effects [MeSH Qualifier]
- analysis [MeSH Qualifier]
- antagonists and inhibitors [MeSH Qualifier]
- biosynthesis [MeSH Qualifier]
- blood [MeSH Qualifier]
- cerebrospinal fluid [MeSH Qualifier]
- chemical synthesis [MeSH Qualifier]
- chemistry [MeSH Qualifier]
- classification [MeSH Qualifier]
- deficiency [MeSH Qualifier]
- drug effects [MeSH Qualifier]
- economics [MeSH Qualifier]
- genetics [MeSH Qualifier]
- history [MeSH Qualifier]
- immunology [MeSH Qualifier]
- isolation and purification [MeSH Qualifier]
- metabolism [MeSH Qualifier]
- pharmacokinetics [MeSH Qualifier]
- pharmacology [MeSH Qualifier]
- physiology [MeSH Qualifier]
- poisoning [MeSH Qualifier]
- radiation effects [MeSH Qualifier]
- standards [MeSH Qualifier]
- supply and distribution [MeSH Qualifier]
- therapeutic use [MeSH Qualifier]
- toxicity [MeSH Qualifier]
- ultrastructure [MeSH Qualifier]
- urine [MeSH Qualifier]
Currated CISMeF NLP mapping
- Angiotensin-Converting Enzyme 2 [NCIt concept]
- angiotensin converting enzyme 2 [COVID-19 Thesaurus concept]
Record concept(s)
- Angiotensin-Converting Enzyme 2 [MeSH concept]
Related MeSH Supplementary Concept(s)
- ACE2 protein, human [MeSH Supplementary Concept]
- Ace2 protein, mouse [MeSH Supplementary Concept]
- Ace2 protein, rat [MeSH Supplementary Concept]
- alunacedase alfa [MeSH Supplementary Concept]
See also
- Receptors, Coronavirus [MeSH Descriptor]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- Angiotensin-Converting Enzyme 2 [NCIt concept]

Keyword's position in hierarchy(ies) :

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