Lysine-Specific Demethylase 6B

Preferred Label : Lysine-Specific Demethylase 6B;

NCIt synonyms : EC 1.14.11.-; Lysine Demethylase 6B; Jumonji Domain-Containing Protein 3; JmjC Domain-Containing Protein 3; Histone Demethylase JMJD3; KDM6B;

NCIt definition : Lysine-specific demethylase 6B (1643 aa, 177 kDa) is encoded by the human KDM6B gene. This protein is involved in both demethylation of histone H3 and regulation of cellular differentiation.;

Details

Origin ID

C80019;

UMLS CUI

C2001242;

OMIM relation
- Lysine demethylase 6b [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- KDM6B protein, human [MeSH Supplementary Concept]
- KDM6B protein, human [MeSH concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- KDM6B Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_biochemical_function
- Chromatin Remodeling Factor [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Macrophage Differentiation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Cell Differentiation Process [NCIt concept]
- Chromatin Remodeling [NCIt concept]
- Developmental Process [NCIt concept]
- Histone Demethylation [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Transcriptional Regulation [NCIt concept]

Keyword's position in hierarchy(ies) :

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