S-Adenosylmethionine Synthase Isoform Type-2

Preferred Label : S-Adenosylmethionine Synthase Isoform Type-2;

NCIt synonyms : Methionine Adenosyltransferase II Alpha; Testicular Tissue Protein Li 121; Methionine Adenosyltransferase 2A; AdoMet Synthetase 2; MAT-II; MAT2A; MAT 2; Methionine Adenosyltransferase II; AdoMet Synthase 2; S-Adenosylmethionine Synthetase 2; Methionine Adenosyltransferase 2;

NCIt definition : S-adenosylmethionine synthase isoform type-2 (395 aa, 44 kDa) is encoded by the human MAT2A gene. This protein plays a role in the synthesis of S-adenosylmethionine from methionine and ATP.;

Détails

Origin ID

C180419;

UMLS CUI

C2352004;

OMIM relation
- Methionine adenosyltransferase II, alpha [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- MAT2A protein, human [MeSH concept]
- Mat2a protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- MAT2A Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Kidney [NCIt concept]
gene_product_has_associated_anatomy
- Cytosol [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
- One Carbon Pool by Folate Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Amino Acid Biosynthesis [NCIt concept]
is_target
- MAT2A Inhibitor AG-270 [NCIt concept]
- MAT2A Inhibitor IDE397 [NCIt concept]
- MAT2A Inhibitor ISM3412 [NCIt concept]
- MAT2A Inhibitor S-095035 [NCIt concept]

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