Histone-Lysine N-Methyltransferase SETD1A

Preferred Label : Histone-Lysine N-Methyltransferase SETD1A;

NCIt synonyms : Lysine N-Methyltransferase 2F; Set1/Ash2 Histone Methyltransferase Complex Subunit SET1; SETD1A; SET Domain-Containing Protein 1A; EC 2.1.1.364; Lysine-Specific Methyltransferase 2F; hSET1A;

NCIt definition : Histone-lysine N-methyltransferase SETD1A (1707 aa, 186 kDa) is encoded by the human SETD1A gene. This protein plays a role in catalyzing mono- and tri-methylation of lysine-4 in histone H3 (H3K4).;

Details

Origin ID

C200410;

OMIM relation
- Set domain-containing protein 1a [OMIM gene]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- SETD1A Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Proline-Rich Domain [NCIt concept]
- RNA Recognition Motif [NCIt concept]
- SET Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysine Degradation Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Chromatin Remodeling [NCIt concept]
- Gene Expression [NCIt concept]
- Histone Methylation [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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