Acetyl-CoA Carboxylase 1

Preferred Label : Acetyl-CoA Carboxylase 1;

NCIt synonyms : Acetyl-Coenzyme A Carboxylase Alpha; ACACA; ACC1; ACC-Alpha; ACC; EC 6.4.1.2;

NCIt definition : Acetyl-CoA carboxylase 1 (2346 aa, 266 kDa) is encoded by the human ACACA gene. This protein plays a role in the modulation of long-chain fatty acid biosynthesis.;

NCIt note : Acetyl-CoA carboxylase 1 has 3 functions; biotin carboxyl carrier protein, biotin carboxylase (EC 6.3.4.14) and carboxyltransferase (EC 6.4.1.2). (UniProt);

Details

Origin ID

C103887;

UMLS CUI

C3541857;

Automatic exact mappings (from CISMeF team)
- Acetyl-coa carboxylase-alpha [OMIM gene]
- Aplasia cutis congenita, nonsyndromic [OMIM Phenotype]
- Biotin carboxylase (substance) [SNOMED CT concept]
- Corpus callosum, agenesis of [OMIM Phenotype]
- acetyl-CoA carboxylase alpha [HGNC gene]
- biotin carboxylase [MeSH concept]
- biotin carboxylase [MeSH Supplementary Concept]
- biotin carboxylase [SNOMED Notion]
OMIM relation
- Acetyl-coa carboxylase-alpha [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- ACACA protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- ACACA Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Ligase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Cytoplasm [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Fatty Acid Biosynthesis Pathway [NCIt concept]
- Insulin Resistance Pathway [NCIt concept]
- Insulin/Insulin Receptor Signaling Pathway [NCIt concept]
- Propanoate Metabolism Pathway [NCIt concept]
- Pyruvate Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Fatty Acid Metabolism [NCIt concept]
- Triglyceride Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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