Cathepsin H - CISMeF

Preferred Label : Cathepsin H;

NCIt synonyms : CPSB; Aleurain; CTSH; Cathepsin B3; Cathepsin BA; CTSH Protein; N-Benzoylarginine-Beta-Naphthylamide Hydrolase; EC 3.4.22.16; MGC1519; Pro-Cathepsin H; Cathepsin-H;

NCIt definition : Pro-cathepsin H (335 aa, 37 kDa) is encoded by the human CTSH gene. This protein plays a role in both degradation of proteins in the lysosome and antigen processing.;

NCIt note : Activated cathepsin H is a lysosomal cysteine protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor.;

Details

Origin ID

C17276;

UMLS CUI

C2603690;

Currated CISMeF NLP mapping
- aleurain [MeSH concept]
- aleurain [MeSH Supplementary Concept]
- cathepsin H [MeSH Descriptor]
- cathepsin H [MeSH concept]
- cathepsin h [SNOMED Notion]
False automatic mappings
- Cathepsin H (substance) [SNOMED CT concept]
OMIM relation
- Cathepsin h [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- CTSH protein, human [MeSH Supplementary Concept]
- CTSH protein, human [MeSH concept]
- Cathepsin H (substance) [SNOMED CT concept]
- cathepsin H [MeSH concept]
- cathepsin H [MeSH Descriptor]
- cathepsin h [SNOMED Notion]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- CTSH Gene [NCIt concept]
- Cysteine Peptidase Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- Peptidase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Lysosome [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Protease Domain [NCIt concept]
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Lysosome Assembly Pathway [NCIt concept]
gene_product_malfunction_associated_with_disease
- Malignant Prostate Neoplasm [NCIt concept]
gene_product_plays_role_in_biological_process
- Hydrolysis [NCIt concept]
- Protein Turnover [NCIt concept]
- Proteolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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