Protein Turnover

Preferred Label : Protein Turnover;

NCIt synonyms : Protein Degradation; Protein Degradation, Metabolic;

NCIt definition : The normal downside of protein steady state metabolism in cells, involving conjugation, transport, oxidation, and proteolysis; not to be confuse with proteolysis, which applies only to peptide bond hydrolysis.;

Details

Origin ID

C21064;

UMLS CUI

C0597297;

Automatic exact mappings (from CISMeF team)
- proteolysis [Artificial nutrition thesaurus concept]
Currated CISMeF NLP mapping
- protein catabolic process [GO term]
- protein degradation [Disease (Nov.)]
- proteolysis [MeSH concept]
- proteolysis [MeSH Descriptor]
Semantic type(s)
- Molecular Function [UMLS semantic type]
biological_process_involves_gene_product
- A Disintegrin and Metalloprotease with Thrombospondin Motifs 9 [NCIt concept]
- Activating Molecule In BECN1-Regulated Autophagy Protein 1 [NCIt concept]
- Beclin-2 [NCIt concept]
- Cathepsin H [NCIt concept]
- Cathepsin L1 [NCIt concept]
- Cathepsin L2 [NCIt concept]
- E3 Ubiquitin-Protein Ligase RBX1 [NCIt concept]
- E3 Ubiquitin-Protein Ligase TRIM13 [NCIt concept]
- FAS-Associated Factor 2 [NCIt concept]
- Prolow-Density Lipoprotein Receptor-Related Protein 1 [NCIt concept]
- Proteasomal Ubiquitin Receptor ADRM1 [NCIt concept]
- Sortilin-Related Receptor [NCIt concept]
- Tubulin-Specific Chaperone Cofactor E-Like Protein [NCIt concept]
- Ubiquitin-Conjugating Enzyme E2 D2 [NCIt concept]
- Ubiquitin-Protein Ligase E3A [NCIt concept]
- Vitamin K-Dependent Protein C [NCIt concept]
biological_process_is_part_of_process
- Biochemical Process [NCIt concept]
biological_process_results_from_biological_process
- Receptor Mediated Endocytosis [NCIt concept]
process_involves_gene
- ADAMTS9 Gene [NCIt concept]
- ADAMTS9 wt Allele [NCIt concept]
- ADRM1 Gene [NCIt concept]
- ADRM1 wt Allele [NCIt concept]
- AMBRA1 Gene [NCIt concept]
- AMBRA1 wt Allele [NCIt concept]
- BECN2 Gene [NCIt concept]
- BECN2 wt Allele [NCIt concept]
- CTSH Gene [NCIt concept]
- CTSH wt Allele [NCIt concept]
- CTSL Gene [NCIt concept]
- CTSL wt Allele [NCIt concept]
- CTSV Gene [NCIt concept]
- CTSV wt Allele [NCIt concept]
- FAF2 Gene [NCIt concept]
- FAF2 wt Allele [NCIt concept]
- FBXW4 Gene [NCIt concept]
- FBXW4 wt Allele [NCIt concept]
- LRP1 Gene [NCIt concept]
- LRP1 wt Allele [NCIt concept]
- PROC Gene [NCIt concept]
- PROC wt Allele [NCIt concept]
- RBX1 Gene [NCIt concept]
- RBX1 wt Allele [NCIt concept]
- SORL1 Gene [NCIt concept]
- SORL1 wt Allele [NCIt concept]
- TBCEL Gene [NCIt concept]
- TBCEL wt Allele [NCIt concept]
- TRIM13 Gene [NCIt concept]
- TRIM13 wt Allele [NCIt concept]
- UBE2D2 Gene [NCIt concept]
- UBE2D2 wt Allele [NCIt concept]
- UBE3A Gene [NCIt concept]
- UBE3A wt Allele [NCIt concept]

Keyword's position in hierarchy(ies) :

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