Flavin-Containing Monooxygenase 3

Preferred Label : Flavin-Containing Monooxygenase 3;

NCIt synonyms : FMO Form 2; Hepatic Flavin-Containing Monooxygenase-3; FMO 3; Flavin Containing Monooxygenase 3; Dimethylaniline Oxidase 3; Flavin-Containing Monooxygenase-3; EC 1.14.13.148; EC 1.14.13.8; FMO II; Trimethylamine Monooxygenase; Hepatic Flavin-Containing Monooxygenase 3; FMO3; Flavin-Containing Dimethylaniline Monooxygenase 3; EC 1.14.13.32; Flavin Containing Dimethylaniline Monoxygenase 3;

NCIt related terms : Dimethylaniline Monooxygenase [N-Oxide-Forming] 3;

NCIt definition : Flavin-containing monooxygenase 3 (532 aa, 60 kDa) is encoded by the human FMO3 gene. This protein is involved in the oxygenation primary aliphatic alkylamines and both secondary and tertiary amines.;

Details

Origin ID

C116954;

UMLS CUI

C3888280;

Automatic exact mappings (from CISMeF team)
- Flavin-containing dimethylaniline monooxygenase 3 [OMIM gene]
- N,N-dimethylaniline monooxygenase activity [GO term]
- dimethylaniline monooxygenase (N-oxide forming) [MeSH Supplementary Concept]
- flavin containing dimethylaniline monoxygenase 3 [ORDO Gene]
- flavin containing dimethylaniline monoxygenase 3 [HGNC gene]
- flavin-containing monooxygenase 3 [MeSH concept]
- tertiary amine monooxygenase [MeSH Supplementary Concept]
OMIM relation
- Flavin-containing dimethylaniline monooxygenase 3 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- FMO3 Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_expressed_in_tissue
- Hepatic Tissue [NCIt concept]
gene_product_has_associated_anatomy
- Membrane of the Endoplasmic Reticulum [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Drug Metabolism by Cytochrome P450 Pathway [NCIt concept]
- Taurine and Hypotaurine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- Drug Metabolism Induction [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Xenobiotic Metabolism [NCIt concept]

Keyword's position in hierarchy(ies) :

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