NAD-Dependent Protein Deacetylase Sirtuin-1

Preferred Label : NAD-Dependent Protein Deacetylase Sirtuin-1;

NCIt synonyms : SIR2-Like Protein 1; EC 3.5.1.-; hSIR2; hSIRT1; NAD-Dependent Deacetylase Sirtuin-1; Regulatory Protein SIR2 Homolog 1; Sirtuin Type 1; SIRT1;

NCIt definition : NAD-dependent protein deacetylase sirtuin-1 (747 aa, 82 kDa) is encoded by the human SIRT1 gene. This protein may be involved in protein deacetylation.;

Details

Origin ID

C80115;

UMLS CUI

C1101544;

False automatic mappings
- arylalkyl acylamidase [MeSH Supplementary Concept]
OMIM relation
- Sirtuin 1 [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- SIRT1 protein, human [MeSH concept]
- SIRT1 protein, human [MeSH Supplementary Concept]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- Hydrolase Gene [NCIt concept]
- SIRT1 Gene [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Repair [NCIt concept]
- DNA Replication [NCIt concept]
- Deacetylation [NCIt concept]
- Epigenetic Silencing [NCIt concept]
- Hydrolysis [NCIt concept]

Keyword's position in hierarchy(ies) :

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