DNA (Cytosine-5)-Methyltransferase 3A

Preferred Label : DNA (Cytosine-5)-Methyltransferase 3A;

NCIt synonyms : EC 2.1.1.37; DNMT3A; DNA MTase HsaIIIA; M.HsaIIIA; DNA Methyltransferase HsaIIIA; DNA Cytosine-5-Methyltransferase 3A; DNA Methyltransferase 3A;

NCIt definition : DNA (cytosine-5)-methyltransferase 3A protein (909 aa, 102 kDa) is encoded by the human DNMT3A gene. This soluble, nuclear protein is involved in epigenetic modification of chromatin, catalyzing the methylation of C5 in CpG dinucleotides within DNA.;

Details

Origin ID

C73691;

UMLS CUI

C2348048;

OMIM relation
- Dna methyltransferase 3a [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- DNMT3A Gene [NCIt concept]
- Enzyme Gene [NCIt concept]
- Methyltransferase Gene [NCIt concept]
- Transferase Gene [NCIt concept]
gene_product_has_associated_anatomy
- Nucleus [NCIt concept]
gene_product_has_gene_product_variant
- DNMT3A NP_072046.2:p.P904L [NCIt concept]
- DNMT3A Protein Variant [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_is_element_in_pathway
- Cysteine and Methionine Metabolism Pathway [NCIt concept]
gene_product_plays_role_in_biological_process
- DNA Methylation [NCIt concept]
- Methylation [NCIt concept]

Keyword's position in hierarchy(ies) :

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