Protein-Lysine 6-Oxidase

Preferred Label : Protein-Lysine 6-Oxidase;

NCIt synonyms : Lysyl Oxidase; EC 1.4.3.13; LOX; Protein-Lysine-6-Oxidase;

NCIt definition : Protein-lysine 6-oxidase (417 aa, 47 kDa) is encoded by the human LOX gene. This protein plays a role in both lysine metabolism and the formation of cross-links in extracellular matrix proteins.;

NCI Metathesaurus CUI : CL964377;

Details

Origin ID

C26327;

UMLS CUI

C4743246;

Currated CISMeF NLP mapping
- Protein-Lysine 6-Oxidase [MeSH concept]
- protein-lysine 6-oxidase [MeSH Descriptor]
- protein-lysine 6-oxidase [SNOMED Notion]
False automatic mappings
- Protein-lysine 6-oxidase (substance) [SNOMED CT concept]
OMIM relation
- Lysyl oxidase [OMIM gene]
Semantic type(s)
- Amino Acid, Peptide, or Protein [UMLS semantic type]
- Enzyme [UMLS semantic type]
UMLS correspondences (same concept)
- LOX protein, human [MeSH Supplementary Concept]
- Protein-Lysine 6-Oxidase [MeSH concept]
- Protein-lysine 6-oxidase (substance) [SNOMED CT concept]
- protein-lysine 6-oxidase [SNOMED Notion]
- protein-lysine 6-oxidase [MeSH Descriptor]
concept_is_in_subset
- CTRP Biomarker Terminology [NCIt concept]
- CTRP Molecular Genetic Biomarker Terminology [NCIt concept]
- CTRP Terminology [NCIt concept]
gene_encodes_gene_product
- Enzyme Gene [NCIt concept]
- LOX Gene [NCIt concept]
- Oxidoreductase Gene [NCIt concept]
gene_product_has_organism_source
- Human [NCIt concept]
gene_product_has_structural_domain_or_motif
- Substrate Interaction Domain [NCIt concept]
gene_product_malfunction_associated_with_disease
- Colon Neoplasm [NCIt concept]
gene_product_plays_role_in_biological_process
- Morphogenesis [NCIt concept]
- Oxidation [NCIt concept]
- Oxidation/Reduction [NCIt concept]
- Protein-Protein Interaction [NCIt concept]
is_target
- Pan-LOX Inhibitor PXS-5505 [NCIt concept]

Keyword's position in hierarchy(ies) :

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